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CD141 polyclonal antibody

Product Specifications

Background

CD141/Thrombomodulin (TM, THBD, BDCA-3) is an integral membrane protein expressed on the surface of endothelial cells. Acting as a cofactor with Thrombin, CD141/Thrombomodulin activates and initiates the Protein C anticoagulant pathway. CD141/Thrombomodulin is expressed by a small subset of human CD11c+ myeloid dendritic cells. These CD141+XCR1+ dendritic cells cross-present antigens to naïve CD8+ T cells, priming them to become activated cytotoxic CD8+ T cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM

Swiss Prot

P07204

Reactivity

Human

Immunogen

Recombinant protein of human CD141.

Conjugation

Unconjugated

Applications

IF

Dilution

IF: 1:100~1:500

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CD141 polyclonal antibody detects endogenous levels of CD141 protein.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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