CD131 polyclonal antibody
Product Specifications
Background
The common beta-chain (beta-c) of the granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5 receptors is the major signaling subunit of these receptors, coupling ligand binding to multiple biological activities. Tyrosine phosphorylation of cytokine receptor common beta-chain is one of the first events in GM-CSF, IL-3 and IL-5 receptor activation and in signaling initiation. Serine phosphorylation within the 14-3-3 binding sequence of the common beta-chain is also involved in GM-CSF, IL-3 and IL-5 receptor-specific functions.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; CSF2RB; IL3RB; IL5RB
Swiss Prot
P32927
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human CD131.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:1000~1:2000 IF: 1:100~1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 130 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD131 polyclonal antibody detects endogenous levels of CD131 protein.
Applications Notes
Western blot (WB) analysis of CD131 polyclonal antibody at 1:1000 dilution Lane1:Jurkat whole cell lysate (30ug) Lane2:The Liver tissue lysate of Mouse (30ug)
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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