Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

C1R polyclonal antibody

Product Specifications

Background

The complement component proteins, C1, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation, and cellular chemotaxis. C1q, together with proenzymes C1r and C1s, yield C1, the first component of the classical pathways of the serum complement system. C1 consists of a calcium dependent trimolecular complex of C1r, C1s and C1q in a 2:2:1 ratio. C1r is a dimer formed of two identical chains that are activated by cleavage into two chains, A and B.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Complement C1r subcomponent; Complement component 1 subcomponent r; Complement C1r subcomponent light chain; C1R

Swiss Prot

P00736

Reactivity

Human, Mouse, Rat

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Complement C1R.

Conjugation

Unconjugated

Applications

WB, IF/ICC

Dilution

WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 55 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

C1R polyclonal antibody detects endogenous levels of C1R protein.

Applications Notes

Western blot analysis of Complement C1R expression in Hela (A), A549 (B), mouse liver (C), rat liver (D) whole cell lysates.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Z-trans-2-aminocyclohexanecarboxylic acid 99+% (HPLC)
242922-01 250 mg

Z-trans-2-aminocyclohexanecarboxylic acid 99+% (HPLC)

Sign In for Pricing
View Details
Z-trans-2-aminocyclohexanecarboxylic acid 99+% (HPLC)
242922-02 1 g

Z-trans-2-aminocyclohexanecarboxylic acid 99+% (HPLC)

Sign In for Pricing
View Details
Z-trans-2-aminocyclohexanecarboxylic acid 99+% (HPLC)
242922-03 5 g

Z-trans-2-aminocyclohexanecarboxylic acid 99+% (HPLC)

Sign In for Pricing
View Details
CREB3L4 Protein Vector (Human) (pPB-C-His)
PV010653 500 ng

CREB3L4 Protein Vector (Human) (pPB-C-His)

Sign In for Pricing
View Details
RPE65 Antibody Blocking Peptide
orb1500425 500 µg

RPE65 Antibody Blocking Peptide

Sign In for Pricing
View Details
Mucin-1/MUC1, Human (357a.a, HEK293, Fc)
HY-P78740-01 5 µg

Mucin-1/MUC1, Human (357a.a, HEK293, Fc)

Sign In for Pricing
View Details