Phospho-JAK2-Y1007/1008 polyclonal antibody
Product Specifications
Background
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
JAK2; JTK10; THCYT3
Swiss Prot
O60674
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphorylated peptide around Y1007 & Y1008 of human JAK2 (NP_004963.1?) .
Conjugation
Unconjugated
Applications
WB, IHC IF IP
Dilution
WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF: 1:100 - 1:500|IP: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylated
Molecular Weight
131KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phosphorylated Antibodies
Applications Notes
Western blot (WB) analysis of Phospho-JAK2-Y1007/1008 polyclonal antibody at 1:1000 dilution Lane1:K562 treated with GM-CSF (100 ng/ml) at 37°C for 15 minutes whole cell lysate (30ug) Lane2:K562 whole cell lysate (30ug)
Host or Source
Rabbit
Available Sizes
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