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Phospho-JAK2-Y1007/1008 polyclonal antibody

Product Specifications

Background

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

JAK2; JTK10; THCYT3

Swiss Prot

O60674

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic phosphorylated peptide around Y1007 & Y1008 of human JAK2 (NP_004963.1?) .

Conjugation

Unconjugated

Applications

WB, IHC IF IP

Dilution

WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF: 1:100 - 1:500|IP: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Phosphorylated

Molecular Weight

131KDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Phosphorylated Antibodies

Applications Notes

Western blot (WB) analysis of Phospho-JAK2-Y1007/1008 polyclonal antibody at 1:1000 dilution Lane1:K562 treated with GM-CSF (100 ng/ml) at 37°C for 15 minutes whole cell lysate (30ug) Lane2:K562 whole cell lysate (30ug)

Host or Source

Rabbit

Available Sizes

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