TBX1 mouse monoclonal antibody

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

T-box transcription factor TBX1; T-box protein 1; Testis-specific T-box protein; TBX1 ; 9606 NCBI; Homo sapiens (Human)

Swiss Prot

O43435

Reactivity

Human, Mouse, Rat

Immunogen

Full length human recombinant protein of human TBX1 (NP_542377) produced in HEK293T cell.

Conjugation

Unconjugated

Applications

IHC, WB

Dilution

WB 1:4000, IHC 1:150

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .