TBX1 mouse monoclonal antibody
Product Specifications
Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
T-box transcription factor TBX1; T-box protein 1; Testis-specific T-box protein; TBX1 ; 9606 NCBI; Homo sapiens (Human)
Swiss Prot
O43435
Reactivity
Human, Mouse, Rat
Immunogen
Full length human recombinant protein of human TBX1 (NP_542377) produced in HEK293T cell.
Conjugation
Unconjugated
Applications
IHC, WB
Dilution
WB 1:4000, IHC 1:150
Purity
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 43 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Western blot (WB) analysis of TBX1 mouse monoclonal antibody at 1:500 dilution Lane1:HEK293 whole cell lysate (30ug)
Host or Source
Mouse
Available Sizes
Curated Selection
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