PRODH mouse monoclonal antibody

Product Specifications

Background

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4) . This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Proline dehydrogenase; EC:1.5.5.2 (UniProtKB | ENZYME | Rhea) ; PRODH ; Proline oxidase ; TtPRODH; TT_C1214; 262724 NCBIThermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)

Swiss Prot

O43272

Reactivity

Human, Mouse

Immunogen

Full length human recombinant protein of human PRODH (NP_057419) produced in E.coli.

Conjugation

Unconjugated

Applications

IHC, WB

Dilution

WB 1:2000, IHC 1:500

Purity

The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodified

Molecular Weight

~ 68 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG1

Applications Notes

Western blot (WB) analysis of PRODH mouse monoclonal antibody at 1:500 dilution Lane1:The Kidney tissue lysate of Rat (30ug) Lane2:The Liver tissue lysate of Mouse (30ug) Lane3:The heart tissue lysate of Mouse (30ug)