TRIM24 mouse monoclonal antibody
Product Specifications
Background
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Transcription intermediary factor 1-alpha; EC:2.3.2.27 ; TIF1-alpha; E3 ubiquitin-protein ligase Trim24; RING-type E3 ubiquitin transferase TIF1-alpha ; Tripartite motif-containing protein 24
Swiss Prot
O15164
Reactivity
Human, Mouse
Immunogen
Human recombinant protein fragment corresponding to amino acids 706-1016 of human TRIM24 (NP_003843) produced in E.coli.
Conjugation
Unconjugated
Applications
IHC, WB
Dilution
WB 1:2000, IHC 1:150
Purity
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 117 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG1
Applications Notes
Western blot (WB) analysis of TRIM24 mouse monoclonal antibody at 1:500 dilution Lane1:COS-7 whole cell lysate (30ug)
Host or Source
Mouse
Available Sizes
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