Photosensitizer-6
Photosensitizer-6 (Compound 4) is a gold (I) complex and exhibits inhibitory activity against TrxR. Photosensitizer-6 induces apoptosis in 4T1 cell, targets and eradicates tumors through chemo-phototherapy and immunogenic cell death under light exposure. Photosensitizer-6 can be used for tumor imaging[1].
Product Specifications
CAS Number
3052251-17-6
UNSPSC
12352005
Target
Apoptosis; TrxR
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/photosensitizer-6.html
Smiles
FP(F)(F)(F)(F)F.C1(N(C2=CC=C(C3=CC=C(C4=CC=[N]([Au][P](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)C=C4)C8=NSN=C83)C=C2)C9=CC=CC=C9)=CC=CC=C1
Molecular Formula
C47H35AuF6N4P2S
Molecular Weight
1060.78
References & Citations
[1]Feng N, et al., Strategically engineered Au (I) complexes for orchestrated tumor eradication via chemo-phototherapy and induced immunogenic cell death. Nat Commun. 2024 Sep 18;15 (1) :8187.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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