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Photosensitizer-6

Photosensitizer-6 (Compound 4) is a gold (I) complex and exhibits inhibitory activity against TrxR. Photosensitizer-6 induces apoptosis in 4T1 cell, targets and eradicates tumors through chemo-phototherapy and immunogenic cell death under light exposure. Photosensitizer-6 can be used for tumor imaging[1].

Product Specifications

CAS Number

3052251-17-6

UNSPSC

12352005

Target

Apoptosis; TrxR

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/photosensitizer-6.html

Smiles

FP(F)(F)(F)(F)F.C1(N(C2=CC=C(C3=CC=C(C4=CC=[N]([Au][P](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)C=C4)C8=NSN=C83)C=C2)C9=CC=CC=C9)=CC=CC=C1

Molecular Formula

C47H35AuF6N4P2S

Molecular Weight

1060.78

References & Citations

[1]Feng N, et al., Strategically engineered Au (I) complexes for orchestrated tumor eradication via chemo-phototherapy and induced immunogenic cell death. Nat Commun. 2024 Sep 18;15 (1) :8187.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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