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Buclizine (dihydrochloride) (Standard)

Buclizine (dihydrochloride) (Standard) is the analytical standard of Buclizine (dihydrochloride) . This product is intended for research and analytical applications. Buclizine dihydrochloride is an orally active antihistamine antiallergic compound. Buclizine dihydrochloride is a potent teratogen in the rat and shows anti-tumor activity[1][2][3].

Product Specifications

CAS Number

129-74-8

UNSPSC

12352005

Target

Histamine Receptor; Reference Standards

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/buclizine-dihydrochloride-standard.html

Smiles

CC(C1=CC=C(CN2CCN(C(C3=CC=C(Cl)C=C3)C4=CC=CC=C4)CC2)C=C1)(C)C.[H]Cl.[H]Cl

Molecular Formula

C28H35Cl3N2

Molecular Weight

505.95

References & Citations

[1]Gamal A E Mostafa, et al. Buclizine. Profiles Drug Subst Excip Relat Methodol. 2011;36:1-33.|[2]Ean-Jeong Seo, et al. Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy. Oncotarget. 2016 Mar 29;7 (13) :16818-39.|[3]C T King, et al. Teratogenic effect of buclizine and hydroxyzine in the rat and chlorcyclizine in the mouse. Am J Obstet Gynecol. 1966 May 1;95 (1) :109-11.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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