Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 44.9 kDa. The protein migrates as 52-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Immobilized Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag (Cat. No. NEE-V524p) at 1 μg/mL (100 μL/well) can bind Anti-NA(A/PAN) Antibody,Mouse IgG with a linear range of 0.1-2 ng/mL (QC tested).