SDPC

SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research[1].

Product Specifications

CAS Number

[59403-52-0]

Product Name Alternative

PC (18:0/22:6) ; DHA-PC; 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine

UNSPSC

12352200

Hazard Statement

H302, H310, H315, H319, H331, H351, H361, H372

Target

PPAR

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/1-stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Molecular Formula

C48H84NO8P

Molecular Weight

834.16

Precautions

H302, H310, H315, H319, H331, H351, H361, H372

References & Citations

[1]Yuanyuan Liu, et al. DHA-enriched phosphatidylcholine suppressed angiogenesis by activating PPARγ and modulating the VEGFR2/Ras/ERK pathway in human umbilical vein endothelial cells. Food Sci Biotechnol. 2021 Oct 27;30 (12) :1543-1553.