PW0729
PW0729 (compound 15b) is an orphan GPR52 agonist with potential applications in GPR52 activation, signaling bias, and neuropsychiatric and neurological disorders. The brain exposure characteristics of PW0729 need to be further optimized[1].
Product Specifications
CAS Number
[2767348-36-5]
UNSPSC
12352005
Target
GPR52
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pw0729.html
Smiles
O=C(C1=CC=CC(NC2=CC(CC3=CC=CC(C(F)(F)F)=C3)=CC=N2)=C1C)NCCO
Molecular Formula
C23H22F3N3O2
Molecular Weight
429.43
References & Citations
[1]Murphy R E, Wang P, Ali S, et al. Discovery of 3- ((4-Benzylpyridin-2-yl) amino) benzamides as Potent GPR52 G Protein-Biased Agonists[J]. Journal of Medicinal Chemistry, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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