C450-0730
Product Specifications
UNSPSC Description
C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/c450-0730.html
Purity
97.0
Smiles
CC(C)CC(NS(=O)(C1=CC2=C(N(C(C)=O)CC2)C=C1)=O)C(NCC3=CC=C(Cl)C=C3)=O
Molecular Weight
478.00
References & Citations
[1]Swem LR, et al. Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi. Cell. 2008 Aug 8;134(3):461-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117005/C450-0730-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117005/C450-0730-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1036730-46-7
Available Sizes
Curated Selection
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