1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran
Product Specifications
UNSPSC Description
1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC50 of 28 μM, inhibits malondialdehyde (MDA) with the IC50 of 71 μM, and inhibits α-glucosidase with the IC50 of 6.22 μM[1].
Target Antigen
Reactive Oxygen Species
Type
Natural Products
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/1-2-diacetoxy-4-7-8-trihydroxy-3-4-hydroxyphenyl-dibenzofuran.html
Solubility
10 mM in DMSO
Smiles
O=C(C)OC1=C(C2=C(C(O)=C1C3=CC=C(O)C=C3)OC4=CC(O)=C(C=C42)O)OC(C)=O
Molecular Weight
424.36
References & Citations
[1]Ke Ma et al. Two sarcoviolins with antioxidative and α-glucosidase inhibitory activity from the edible mushroom <i>Sarcodon leucopus</i> collected in Tibet. J Nat Prod. 2014 Apr 25;77(4):942-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N9283/1-2-Diacetoxy-4-7-8-trihydroxy-3-4-hydroxyphenyl-dibenzofuran-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9283/
Clinical Information
No Development Reported
CAS Number
146905-24-0
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