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PAz-PC

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were isolated and purified from oxLDL and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. PAz-PC (Azelaoyl PC) is one of the predominant oxLDL species and may be one of the important structural determinants of oxLDL.

Product Specifications

CAS Number

[117746-89-1]

Product Name Alternative

PAzePC; Azelaoyl PC; 1-Palmitoyl-2-Azelaoyl PC

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/paz-pc.html

Concentration

15.02 mM * 100 μL in Ethanol

Purity

99.9

Smiles

CCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCC(O)=O)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Molecular Formula

C33H64NO10P

Molecular Weight

665.84

Precautions

H225, H319

References & Citations

[1]Podrez, et al. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. J. Clin. Invest. 105 (8), 1095-1108 (2000) .

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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