AIF [SZ05-01] Antibody

A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl-2 family proteins, resulting in the release of several proteins from the mitochondrial intermembrane space. Several of these proteins participate in apoptosis, including cytochrome c, procaspases 2, 3, and 9, and AIF (apoptosis-inducing factor) . AIF has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIF from mitochondria, but not to block its apoptogenic activity.

Product Specifications

Immunogen

Recombinant protein

Product Datasheet

https://www.omnimabs.com/view/goto.aspx?viewtype=getproductmanual&id=188018

Antibody Type

Primary Antibodies

Product Name Synonym

AIFM1 antibody AIFM1_HUMAN antibody Apoptosis inducing factor 1, mitochondrial antibody Apoptosis inducing factor antibody Apoptosis inducing factor, mitochondrion associated, 1 antibody Apoptosis-inducing factor 1 antibody CMTX4 antibody COWCK antibody COXPD6 antibody Harlequin antibody Hq antibody mAIF antibody MGC111425 antibody MGC5706 antibody mitochondrial antibody Neuropathy, axonal motor-sensory, with deafness and mental retardation antibody neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome) antibody PDCD 8 antibody PDCD8 antibody Programmed cell death 8 (apoptosis inducing factor) antibody Programmed cell death 8 antibody Programmed cell death 8 isoform 1 antibody Programmed cell death 8 isoform 2 antibody Programmed cell death 8 isoform 3 antibody Programmed cell death protein 8 antibody Programmed cell death protein 8 mitochondrial antibody Programmed cell death protein 8 mitochondrial precursor antibody Programmed cell death protein 8 mitochondrial precursor antibody Striatal apoptosis inducing factor antibody