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AChE-IN-23

AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1].

Product Specifications

CAS Number

6297-14-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-23.html

Purity

99.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(N)C=C1CN(CC)CC.[H]Cl.[H]Cl

Molecular Formula

C11H20Cl2N2O

Molecular Weight

267.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Martijn Constantijn de Koning, et al. Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. Eur J Med Chem. 2018 Sep 5;157:151-160.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE

Available Sizes

Frequently Asked Questions

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