AChE-IN-23
AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1].
Product Specifications
CAS Number
[6297-14-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-23.html
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(N)C=C1CN(CC)CC.[H]Cl.[H]Cl
Molecular Formula
C11H20Cl2N2O
Molecular Weight
267.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Martijn Constantijn de Koning, et al. Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. Eur J Med Chem. 2018 Sep 5;157:151-160.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Curated Selection
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