Dimethomorph

Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM[1][2][3].

Product Specifications

CAS Number

[110488-70-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Androgen Receptor; Fungal; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dimethomorph.html

Purity

99.13

Solubility

DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1CCOCC1)/C=C(C2=CC=C(Cl)C=C2)\C3=CC=C(OC)C(OC)=C3

Molecular Formula

C21H22ClNO4

Molecular Weight

387.86

Precautions

H302, H315, H319, H335

References & Citations

[1]M E Matheron, et al. Impact of Azoxystrobin, Dimethomorph, Fluazinam, Fosetyl-Al, and Metalaxyl on Growth, Sporulation, and Zoospore Cyst Germination of Three Phytophthora spp. Plant Dis. 2000 Apr;84 (4) :454-458.|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119 (6) :794-800.|[3]Yigal Cohen, , et al. Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans. Phytopathology. 2007 Oct;97 (10) :1274-83.