Amodiaquine-d10
Amodiaquine-d10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4].
Product Specifications
CAS Number
1189449-70-4
UNSPSC
12352005
Hazard Statement
H302
Target
Histone Methyltransferase; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Epigenetics
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Purity
97.0
Solubility
10 mM in DMSO|DMSO : 66.67mg/mL (ultrasonic; adjust pH to 3 with 1M HCl)
Smiles
ClC(C=C1)=CC2=C1C(NC3=CC(CN(C([2H])([2H])C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])=C(C=C3)O)=CC=N2
Molecular Formula
C20H12D10ClN3O
Molecular Weight
365.92
Precautions
P264-P270-P330-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
Plasmodium
Frequently Asked Questions
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