Metaproterenol

Metaproterenol (Orciprenaline) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol also has anti-inflammatory activity[1][2].

Product Specifications

CAS Number

[586-06-1]

Product Name Alternative

Orciprenaline

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology; Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/metaproterenol.html

Solubility

10 mM in DMSO

Smiles

OC1=CC(C(O)CNC(C)C)=CC(O)=C1

Molecular Formula

C11H17NO3

Molecular Weight

211.26

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92 (1) :101-113.|[2]Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34 (1) :77-83.