Guanethidine
Product Specifications
UNSPSC Description
Guanethidine sulphate was synthesized in 1959. Guanethidine is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres.
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/guanethidine.html
Solubility
10 mM in DMSO
Smiles
NC(NCCN1CCCCCCC1)=N
Molecular Weight
198.31
References & Citations
[1]P Dubový, etal. Local chemical sympathectomy of rat bone marrow and its effect on marrow cell composition.|[2]Waldiceu A.VerriJr, etal. Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Beha
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1251/Guanethidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1251/
Clinical Information
Launched
CAS Number
55-65-2
Curated Selection
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