Tiapride
Tiapride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride shows anti-dyskinetic activity and anxiolytic activity. Tiapride is a neuroleptic agent[1][2].
Product Specifications
CAS Number
51012-32-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tiapride.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCN(CC)CC)C1=CC(S(=O)(C)=O)=CC=C1OC
Molecular Formula
C15H24N2O4S
Molecular Weight
328.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Scatton B, et al. The preclinical pharmacologic profile of tiapride. Eur Psychiatry. 2001 Jan;16 Suppl 1:29s-34s.|[2]Peters DH, et al. Tiapride. A review of its pharmacology and therapeutic potential in the management of alcohol dependence syndrome. Drugs. 1994 Jun;47 (6) :1010-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
D2 Receptor; D3 Receptor
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