Nitroxoline-d4
Nitroxoline-d4 is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].
Product Specifications
Product Name Alternative
8-Hydroxy-5-nitroquinoline-D4; 5-Nitro-8-quinolinol-D4
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy
Field of Research
Infection; Cancer
Purity
0.999
Solubility
10 mM in DMSO
Smiles
OC1=C2N=C([2H])C([2H])=C([2H])C2=C([N+]([O-])=O)C=C1[2H]
Molecular Formula
C9H2D4N2O3
Molecular Weight
194.18
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Abouelhassan Y, et al. Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria. Int J Antimicrob Agents. 2017 Feb;49 (2) :247-251.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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