Climbazole-d4
Product Specifications
UNSPSC Description
Climbazole-d4 is the deuterium labeled Climbazole. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].
Target Antigen
Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Others
Field of Research
Infection
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC(C([2H])=C1[2H])=C([2H])C([2H])=C1OC(N2C=CN=C2)C(C(C)(C)C)=O
Molecular Weight
296.79
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161.|[3]Y Kobayashi, et al. Climbazole is a new potent inducer of rat hepatic cytochrome P450. J Toxicol Sci. 2001 Aug;26(3):141-50.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
1185117-79-6
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