Climbazole-d4

Climbazole-d4 is the deuterium labeled Climbazole. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].

Product Specifications

CAS Number

[1185117-79-6]

Product Name Alternative

BAY-e 6975-d4

UNSPSC

12352005

Hazard Statement

H302

Target

Fungal; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC(C([2H])=C1[2H])=C([2H])C([2H])=C1OC(N2C=CN=C2)C(C(C)(C)C)=O

Molecular Formula

C15H13D4ClN2O2

Molecular Weight

296.79

Precautions

H302

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8 (1) :8161.|[3]Y Kobayashi, et al. Climbazole is a new potent inducer of rat hepatic cytochrome P450. J Toxicol Sci. 2001 Aug;26 (3) :141-50.