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Antazoline

Product Specifications

UNSPSC Description

Antazoline (Phenazoline) is an H1 receptor antagonist that affects the activity of the central nervous system, has a potent antiarrhythmic effect[1][2][3].

Target Antigen

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/antazoline.html

Purity

99.70

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1

Molecular Weight

265.35

References & Citations

[1]Maciej T Wybraniec, et al. Efficacy and safety of antazoline for cardioversion of atrial fibrillation: propensity score matching analysis of a multicenter registry (CANT II Study). Pol Arch Intern Med. 2022 Jun 29;132(6):16234.|[2]Jing Li, et al. Repurposing of Antazoline Hydrochloride as an Inhibitor of Hepatitis B Virus DNA Secretion. Virol Sin. 2021 Jun;36(3):501-509.|[3]MariuszŚwiąder,et al. Influence of antazoline and ketotifen on the anticonvulsant activity of conventional antiepileptics against maximal electroshock in mice. Eur Neuropsychopharmacol. 2004 Aug;14(4):307-18.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B1067A/Antazoline-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B1067A/Antazoline-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

91-75-8

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