Benfluorex
Product Specifications
UNSPSC Description
Benfluorex (JP-992) is a hepatic nuclear factor 4 alpha (HNF4α) activator.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Benfluorex.html
Solubility
10 mM in DMSO
Smiles
FC(C1=CC(CC(NCCOC(C2=CC=CC=C2)=O)C)=CC=C1)(F)F
Molecular Weight
351.36
References & Citations
[1]Lee SH, et al. Identification of alverine and benfluorex as HNF4α activators. ACS Chem Biol. 2013 Aug 16;8(8):1730-6.|[2]Kohl C, et al. Effects of benfluorex on fatty acid and glucose metabolism in isolated rat hepatocytes: from metabolic fluxes to gene expression. Diabetes. 2002 Aug;51(8):2363-8.Biochem Pharmacol. 6 August 2022, 115198.|EBioMedicine. 2022 Jul 28;82:104181.|Research Square Print. December 19th, 2022.|Adv Sci (Weinh). 2024 Jul 5:e2403451.|Virol J. 2021 Sep 28;18(1):196.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1058A/Benfluorex-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1058A/
Clinical Information
Launched
CAS Number
23602-78-0
Curated Selection
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