Penicillin V-d5 (potassium)

Penicillin V-d5 (potassium) is the deuterium labeled Penicillin V Potassium[1]. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis[2][3][4][5].

Product Specifications

CAS Number

[2699607-22-0]

Product Name Alternative

Phenoxymethylpenicillin-d5 (potassium salt)

UNSPSC

12352005

Hazard Statement

H302, H317, H334

Target

Antibiotic; Bacterial

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

98.10

Solubility

DMSO : 12 mg/mL (ultrasonic; warming)

Smiles

O=C([C@@H]1N2[C@@](SC1(C)C)([H])[C@@H](C2=O)NC(COC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O)O[K]

Molecular Formula

C16H12D5KN2O5S

Molecular Weight

393.51

Precautions

H302, H317, H334

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Sabath LD. Et, al. Phenoxymethylpenicillin (penicillin V) and phenethicillin. Med Clin North Am. 1970 Sep;54 (5) :1101-11.|[3]Kamme C, et, al. In vitro effect on group A streptococci of loracarbef versus cefadroxil, cefaclor and penicillin V. Scand J Infect Dis. 199325 (1) :37-42.|[4]Norén T, et, al. In vitro susceptibility to 17 antimicrobials of clinical Clostridium difficile isolates collected in 1993-2007 in Sweden. Clin Microbiol Infect. 2010 Aug16 (8) :1104-10.|[5]Overbosch D, et, al. Comparative pharmacodynamics and clinical pharmacokinetics of phenoxymethylpenicillin and pheneticillin. Br J Clin Pharmacol. 1985 May19 (5) :657-68.|[6]Hermansson A, et, al. Prevention of experimental acute otitis media with penicillin V. Acta Otolaryngol. Jan-Feb 1990109 (1-2) :119-23.