Oxacillin
Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[1].
Product Specifications
CAS Number
[66-79-5]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oxacillin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(C)ON=C3C4=CC=CC=C4)=O)N1C2=O)O
Molecular Formula
C19H19N3O5S
Molecular Weight
401.44
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]KIRBY WM, et al. Oxacillin: laboratory and clinical evaluation. JAMA. 1962 Sep 1;181:739-44.|[2]Yurchenco JA, et al. Nafcillin and oxacillin: comparative antistaphylococcal activity in mice. J Antibiot (Tokyo) . 1976 Apr;29 (4) :460-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Curr Microbiol. 2023 May 31;80 (7) :230.|Microorganisms. 2024 Jan 25;12 (2) :256.|ACS Omega. 2022 Mar 3;7 (10) :9004-9014.|AMB Express. 2024 Dec 24;14 (1) :141.|bioRxiv. 2024 May 10.|bioRxiv. 2025 Oct 27.|BMC Microbiol. 2023 Apr 20;23 (1) :109.|Emerg Microbes Infect. 2024 Dec;13 (1) :2321981.|iScience. 2022 Jan 5;25 (2) :103731.|Microbiol Spectr. 2022 Apr 27;10 (2) :e0054121.|Research Square Print. December 5th, 2022.|Biomed Res Int. 2018 Jul 2:2018:3579832.|Front Microbiol. 2020 Jul 31:11:1720.
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