Tilmicosin-d3
Product Specifications
UNSPSC Description
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects[1][2].
Target Antigen
Antibiotic; Apoptosis; Bacterial; COX; Isotope-Labeled Compounds; NO Synthase
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Apoptosis;Immunology/Inflammation;Others
Field of Research
Infection; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
C[C@@H]([C@@H](CC1=O)O)[C@H]([C@H](C[C@H](C(/C=C/C(C)=C/[C@H](CO[C@H](O[C@H](C)[C@@H](O)[C@H]2OC)[C@@H]2OC)[C@@H](CC)O1)=O)C)CCN(C[C@H](C)C3)C[C@H]3C)O[C@@](O[C@H](C)[C@@H](O)[C@@H]4N(C)C([2H])([2H])[2H])([H])[C@@H]4O
Molecular Weight
872.15
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Micotil 300 New Animal Drug Application
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
2714486-61-8
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