Glyphosate-d2-1

Glyphosate-d2-1 is the deuterium labeled Glyphosate[1]. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[2].

Product Specifications

UNSPSC

12352211

Target

Apoptosis; Autophagy; Isotope-Labeled Compounds; Necroptosis

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Purity

99.89

Solubility

H2O : 13.89 mg/mL (ultrasonic; warming)

Smiles

OC(C([2H])([2H])NCP(O)(O)=O)=O

Molecular Formula

C3H6D2NO5P

Molecular Weight

171.09

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45 (3) :185-208.|[3]Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec237:124435.