Dinotefuran-d3

Dinotefuran-d3 is the deuterium labeled Dinotefuran[1]. Dinotefuran is an insecticide of the neonicotinoid class, its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors[2].

Product Specifications

CAS Number

[2934813-27-9]

Product Name Alternative

MTI-446-d3

UNSPSC

12352005

Hazard Statement

H332, H410

Target

NAChR; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cardiovascular Disease

Purity

98.71

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])N/C(N[N+]([O-])=O)=N\CC1CCOC1

Molecular Formula

C7H11D3N4O3

Molecular Weight

205.23

Precautions

H332, H410

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Liu T, et al. Biochemical and genetic toxicity of dinotefuran on earthworms (Eisenia fetida) . Chemosphere. 2017 Jun;176:156-164.