Levocetirizine-d4
Levocetirizine-d4 ((R) -Cetirizine-d4) is the deuterium-labeled Levocetirizine (HY-B0814) [1]. Levocetirizine ((R) -Cetirizine) is a third-generation peripheral H1-receptor antagonist. Levocetirizine is an antihistaminic agent which is the R-enantiomer of Cetirizine. Levocetirizine has a higher affinity for the histamine H1-receptor than (S) -Cetirizine and can effectively treat allergic rhinitis and chronic idiopathic urticaria[2].
Product Specifications
CAS Number
[1133210-23-7]
Product Name Alternative
(R) -Cetirizine-d4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.41
Solubility
10 mM in DMSO
Smiles
OC(COC([2H])([2H])C([2H])([2H])N(CC1)CCN1[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl)=O
Molecular Formula
C21H21D4ClN2O3
Molecular Weight
392.91
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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