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Cefotiam (dihydrochloride hydrate)

Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1][2].

Product Specifications

Product Name Alternative

SCE-963 (dihydrochloride hydrate)

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefotiam-dihydrochloride-hydrate.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N12)=C(CSC3=NN=NN3CCN(C)C)CS[C@]2([H])[C@H](NC(CC4=CSC(N)=N4)=O)C1=O)O.[H]Cl.[H]Cl.[x].O

Molecular Formula

C18H25Cl2N9O4S3.xH2O

References & Citations

[1]Iwahi T, et, al. Comparative activities of cefotiam and cefazolin against urinary tract infections with Proteus mirabilis in mice. Antimicrob Agents Chemother. 1980 Aug;18 (2) :257-63.|[2]Watt B, et, al. In-vitro activity of cefotiam against bacteria of clinical interest. J Antimicrob Chemother. 1982 Nov;10 (5) :391-5.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Frequently Asked Questions

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