Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Mitiglinide-d8 (calcium hydrate)

Mitiglinide-d8 calcium hydrate (KAD-1229-d8) is the deuterium labeled Mitiglinide calcium hydrate. Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel) . Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes[1][2].

Product Specifications

UNSPSC

12352005

Target

Potassium Channel

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

[2H]C1=C(C(C([2H])([C@@]([2H])(CC(N2C[C@@]3([C@]([H])(C2)CCCC3)[H])=O)C([O-])=O)[2H])=C(C([2H])=C1[2H])[2H])[2H].O.[0.5Ca2+]

Molecular Formula

C19H18D8CaNO4-

Molecular Weight

380.54

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Y Sunaga, et al. The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide. Eur J Pharmacol. 2001 Nov 9;431 (1) :119-25.|[3]Kiyoshi Ichikawa, et al. Effect of KAD-1229, a novel hypoglycaemic agent, on plasma glucose levels after meal load in type 2 diabetic rats. Clin Exp Pharmacol Physiol. May-Jun 2002;29 (5-6) :423-7.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ULK2 discontinued
543579-01 30ul

ULK2 discontinued

Sign In for Pricing
View Details
ULK2 discontinued
543579-02 100 µL

ULK2 discontinued

Sign In for Pricing
View Details
PMPCB CRISPR Activation Plasmid (m)
sc-428494-ACT 20 µg

PMPCB CRISPR Activation Plasmid (m)

Sign In for Pricing
View Details
Klk5 AAV siRNA Pooled Vector
25839164 1.0 µg

Klk5 AAV siRNA Pooled Vector

Sign In for Pricing
View Details
Human Histone deacetylase 7 ELISA Kit
MBS2886789-01 48 Well

Human Histone deacetylase 7 ELISA Kit

Sign In for Pricing
View Details
Human Histone deacetylase 7 ELISA Kit
MBS2886789-02 96 Well

Human Histone deacetylase 7 ELISA Kit

Sign In for Pricing
View Details