Imidafenacin (hydrochloride)
Product Specifications
UNSPSC Description
Imidafenacin hydrochloride is a potent and selective inhibitor of M3 receptors with a Kb of 0.317 nM[1].
Target Antigen
mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/imidafenacin-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(N)C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3C=CN=C3C.[H]Cl
Molecular Weight
355.86
References & Citations
[1]Miyachi H, et al. Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents. Bioorg Med Chem. 1999 Jun;7(6):1151-61.|[2]Yamazaki T, et al. Imidafenacin has no influence on learning in nucleus basalis of Meynert-lesioned rats. Naunyn Schmiedebergs Arch Pharmacol. 2013 Dec;386(12):1095-102.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0662A/Imidafenacin-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0662A/
Clinical Information
Launched
CAS Number
893421-54-0
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