Eicosapentaenoic Acid-d5

Eicosapentaenoic Acid-d5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid.

Product Specifications

CAS Number

[1197205-73-4]

Product Name Alternative

EPA-d5; Timnodonic acid-d5

UNSPSC

12352211

Hazard Statement

H314

Target

Endogenous Metabolite; Histone Demethylase

Type

Isotope-Labeled Compounds

Related Pathways

Epigenetics; Metabolic Enzyme/Protease

Field of Research

Neurological Disease; Cancer

Concentration

1.63 mM * 2 mL in Ethanol

Purity

99.90

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C([2H])([2H])C([2H])([2H])[2H]

Molecular Formula

C20H25D5O2

Molecular Weight

307.48

Precautions

H314

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Martins, J.G., EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials. J Am Coll Nutr, 2009. 28 (5) : p. 525-42.|[3]Shun-he Wang, et al. Endogenous omega-3 long-chain fatty acid biosynthesis from alpha-linolenic acid is affected by substrate levels, gene expression, and product inhibition. RSC Adv., 2017, 7, 40946-40951.|[4]Miaozhen Pan, et al. Dietary ω-3 polyunsaturated fatty acids are protective for myopia. Proc Natl Acad Sci U S A. 2021 Oct 26;118 (43) :e2104689118.