Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d5 is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid.
Product Specifications
CAS Number
[1197205-73-4]
Product Name Alternative
EPA-d5; Timnodonic acid-d5
UNSPSC
12352211
Hazard Statement
H314
Target
Endogenous Metabolite; Histone Demethylase
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Field of Research
Neurological Disease; Cancer
Concentration
1.63 mM * 2 mL in Ethanol
Purity
99.90
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C([2H])([2H])C([2H])([2H])[2H]
Molecular Formula
C20H25D5O2
Molecular Weight
307.48
Precautions
H314
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Martins, J.G., EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials. J Am Coll Nutr, 2009. 28 (5) : p. 525-42.|[3]Shun-he Wang, et al. Endogenous omega-3 long-chain fatty acid biosynthesis from alpha-linolenic acid is affected by substrate levels, gene expression, and product inhibition. RSC Adv., 2017, 7, 40946-40951.|[4]Miaozhen Pan, et al. Dietary ω-3 polyunsaturated fatty acids are protective for myopia. Proc Natl Acad Sci U S A. 2021 Oct 26;118 (43) :e2104689118.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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