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Triclabendazole-d3

Triclabendazole-d3 is the deuterium labeled Triclabendazole. Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME) -dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica[1][2][3].

Product Specifications

CAS Number

1353867-93-2

Product Name Alternative

CGA89317-d3

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Microtubule/Tubulin; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Cytoskeleton; Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

ClC1=C(C=C(NC(SC([2H])([2H])[2H])=N2)C2=C1)OC(C=CC=C3Cl)=C3Cl

Molecular Formula

C14H6D3Cl3N2OS

Molecular Weight

362.68

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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