Taltirelin-13C,d3
Product Specifications
UNSPSC Description
Taltirelin-13C,d3 (TA-0910-13C,d3) is 13C and deuterated labeled Taltirelin (HY-B0596). Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release).
Target Antigen
Apoptosis; Isotope-Labeled Compounds; Thyroid Hormone Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Others;Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology; Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(N(CCC1)[C@@H]1C(N)=O)[C@@H](NC([C@@H](NC2=O)CC(N2[13C]([2H])([2H])[2H])=O)=O)CC3=CN=CN3
Molecular Weight
409.42
References & Citations
[1]Thirunarayanan N, et al. Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. Front Endocrinol (Lausanne). 2012 Oct 9;3:120.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NBP3-27032 100 µg
Rabbit Monoclonal Carbonic Anhydrase VIII/CA8 Antibody (CA8/8605R)
Ask
View Details 