Deferiprone-d3

Deferiprone-d3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].

Product Specifications

CAS Number

[1346601-82-8]

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H319

Target

Ferroptosis; HCV; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Apoptosis; Others

Applications

Cancer-programmed cell death

Field of Research

Cardiovascular Disease; Cancer

Purity

99.46

Solubility

10 mM in DMSO

Smiles

OC1=C(C)N(C([2H])([2H])[2H])C=CC1=O

Molecular Formula

C7H6D3NO2

Molecular Weight

142.17

Precautions

H302+H312+H332, H315, H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Kontoghiorghes GJ, et al. Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine. Drug Saf. 2003;26 (8) :553-584.