Deferiprone-d3
Deferiprone-d3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].
Product Specifications
CAS Number
1346601-82-8
UNSPSC
12352005
Hazard Statement
H302+H312+H332, H315, H319
Target
Ferroptosis; HCV; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Others
Applications
Cancer-programmed cell death
Field of Research
Cardiovascular Disease; Cancer
Purity
99.46
Solubility
10 mM in DMSO
Smiles
OC1=C(C)N(C([2H])([2H])[2H])C=CC1=O
Molecular Formula
C7H6D3NO2
Molecular Weight
142.17
Precautions
H302+H312+H332, H315, H319
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Kontoghiorghes GJ, et al. Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine. Drug Saf. 2003;26 (8) :553-584.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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