Nafcillin (sodium)
Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections[1][2].
Product Specifications
CAS Number
985-16-0
UNSPSC
12352005
Hazard Statement
H317-H334
Target
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nafcillin-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1N(C2=O)[C@]([C@@H]2NC(C(C3=CC=CC=C3C=C4)=C4OCC)=O)([H])SC1(C)C)O[Na]
Molecular Formula
C21H21N2NaO5S
Molecular Weight
436.46
Precautions
P261-P272-P280-P284-P302+P352-P304+P340-P362+P364-P501
References & Citations
[1]Tan AK, et, al. Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase. Biochem J. 1992 Jan 1;281 (Pt 1) (Pt 1) :191-6.|[2]Palmer DL, et, al. Bacterial wound colonization after broad-spectrum versus narrow-spectrum antibiotics. Ann Thorac Surg. 1995 Mar;59 (3) :626-31.|[3]Lawrence I. Mortin, et al. Rapid Bactericidal Activity of Daptomycin against Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Peritonitis in Mice as Measured with Bioluminescent Bacteria. Antimicrob Agents Chemother. 2007 May; 51 (5) : 1787-1794.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
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