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Ornidazole-13C2,15N2

Ornidazole-13C2,15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease[1][2][3].

Product Specifications

Product Name Alternative

Ro 7-0207-13C2,15N2

UNSPSC

12352005

Target

Antibiotic; Bacterial; Hedgehog; Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ornidazole-13c2-15n2.html

Solubility

10 mM in DMSO

Smiles

[13CH3][13C]1=[15N]C=C([N+]([O-])=O)[15N]1CC(CCl)O

Molecular Formula

C5 13C2H10ClN 15N2O3

Molecular Weight

223.60

References & Citations

[1]Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14 (4) : p. 609-13.|[2]Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128 (4) : p. 856-61.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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