Thiamphenicol-d3-1
Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) [1]. Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) [2][3].
Product Specifications
CAS Number
[1217723-41-5]
Product Name Alternative
Thiophenicol-d3-1; Dextrosulphenidol-d3-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
99.0
Solubility
10 mM in DMSO
Smiles
ClC(Cl)C(N[C@@](C([2H])([2H])O)([2H])[C@@H](C1=CC=C(C=C1)S(C)(=O)=O)O)=O
Molecular Formula
C12H12D3Cl2NO5S
Molecular Weight
359.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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