Trospium (chloride) (Standard)

Trospium (chloride) (Standard) is the analytical standard of Trospium (chloride) . This product is intended for research and analytical applications. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2].

Product Specifications

CAS Number

[10405-02-4]

UNSPSC

12352005

Hazard Statement

H302

Target

MAChR; Reference Standards

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/trospium-chloride-standard.html

Purity

99.95

Solubility

10 mM in DMSO

Smiles

[H][C@@]12CC[C@@](C[C@@H](OC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=O)C2)([H])[N+]15CCCC5.[Cl-]

Molecular Formula

C25H30ClNO3

Molecular Weight

427.96

Precautions

H302

References & Citations

[1]David RP Guay. Trospium chloride: an update on a quaternary anticholinergic for treatment of urge urinary incontinence. Ther Clin Risk Manag. 2005 Jun; 1 (2) : 157–167.|[2]Eric S Rovner, et al. Trospium chloride in the management of overactive bladder. Drugs. 2004;64 (21) :2433-46.