Ciclopirox (olamine) (GMP)

Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].

Product Specifications

CAS Number

[41621-49-2]

Product Name Alternative

Ciclopirox (ethanolamine) (GMP) ; HOE 296 (GMP)

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Bacterial; Ferroptosis; Fungal

Type

GMP Small Molecules

Related Pathways

Anti-infection; Apoptosis

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ciclopirox-olamine-gmp.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C)C=C(C2CCCCC2)N1O.NCCO

Molecular Formula

C14H24N2O3

Molecular Weight

268.35

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Niewerth M, et al. Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother. 2003 Jun;47 (6) :1805-17.|[2]Cai H, et al. High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD. Exp Eye Res. 2019 Aug;185:107641.