Ribavirin-13C5

Ribavirin-13C5 is the 13C-labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.

Product Specifications

CAS Number

[1646818-35-0]

Product Name Alternative

Ribasphere-13C5

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic; HCV; Isotope-Labeled Compounds; RSV

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ribavirin-13c5.html

Solubility

10 mM in DMSO

Smiles

O[13C@@H]1[13C@H](O)[13C@@H]([13CH2]O)O[13C@H]1N2N=C(C(N)=O)N=C2

Molecular Formula

C3 13C5H12N4O5

Molecular Weight

249.17

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Chang J, et al. Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. Antiviral Res. 2011 Jan;89 (1) :26-34|[3]Abdel-Hamid NM, et al. Synergistic Effects of Jerusalem Artichoke in Combination with Pegylated Interferon Alfa-2a and Ribavirin Against Hepatic Fibrosis in Rats. Asian Pac J Cancer Prev. 2016;17 (4) :1979-85.|[4]Refaat B, et al. The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report. BMC Res Notes. 2015 Jun 26;8:265|[5]Savic D, et al. Ribavirin shows immunomodulatory effects on activated microglia. Immunopharmacol Immunotoxicol. 2014 Dec;36 (6) :433-41