Metronidazole-13C2,15N2

Metronidazole-13C2,15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

Product Specifications

CAS Number

[1173020-03-5]

UNSPSC

12352005

Hazard Statement

H341, H350, H373

Target

Antibiotic; Apoptosis; Bacterial; Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Apoptosis; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/metronidazole-13c2-15n2.html

Purity

99.30

Solubility

DMSO : 35 mg/mL (ultrasonic; warming)

Smiles

OCC[15N]1C([N+]([O-])=O)=C[15N]=[13C]1[13CH3]

Molecular Formula

C4 13C2H9N 15N2O3

Molecular Weight

175.13

Precautions

H341, H350, H373

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]In Schaechter, M.; Engleberg, N. C.; DiRita, V. J. et al. Schaechter's Mechanisms of Microbial Disease. Hagerstown, MD: Lippincott Williams & Wilkins. p. 28.|[3]http://www.drugs.com/monograph/metronidazole.html|[4]Cohen, S.H., et al., Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA) . Infect Control Hosp Epidemiol, 2010. 31 (5) : p. 431-55.