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Norgestrel-d6

Norgestrel-d6 is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives. Norgestrel-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2376035-98-0

UNSPSC

12352211

Hazard Statement

H302+H312+H332, H315, H319, H351, H360, H362

Target

Isotope-Labeled Compounds; Progesterone Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology

Purity

99.53

Solubility

10 mM in DMSO

Smiles

O[C@]1(CC[C@]2([C@@]3(CC([2H])(C4=C(C(C([2H])(C[C@@]4([C@]3(CC[C@@]21CC)[H])[2H])[2H])=O)[2H])[2H])[H])[H])C#C

Molecular Formula

C21H22D6O2

Molecular Weight

318.48

Precautions

H302+H312+H332, H315, H319, H351, H360, H362

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gallos, I.D., et al., Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis. Am J Obstet Gynecol, 2010. 203 (6) : p. 547 e1-10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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