5,6-trans-Bimatoprost

5,6-trans-Bimatoprost is the isomer of Bimatoprost (HY-B0191), and can be used as an experimental control. Bimatoprost is a prostaglandin analogue that can be used in studies of ocular hypertension and glaucoma and also has anti-fat formation effects.

Product Specifications

CAS Number

[1163135-95-2]

Product Name Alternative

5,6-trans-AGN 192024

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/5-6-trans-bimatoprost.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC)CCC/C=C/C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O

Molecular Formula

C25H37NO4

Molecular Weight

415.57

Precautions

H315, H319, H335

References & Citations

[1]Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55 (1) :22-7.|[2]Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24 (4) :302-7.